Composite
Part:BBa_K2688024:Design
Designed by: William Briand Group: iGEM18_GO_Paris-Saclay (2018-09-23)
tetO_RBS_ler3
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
Design Notes
The gene ler3 encodes the Ler protein of E. coli 3030-1 (GenBank: EGW78798.1) with a point mutation (A 101 ->T ; encoding Ler3 K34M)
Source
The gene ler3 is a spontaneous mutant (A 101 ->T ; encoding Ler2 K34M) obtained during the cloning of ler2 gene (BBa_K2688019)
The gene ler1 was sequence-optimized and synthetized. Original sequence from (Leh et al. mBIO, 2017).